What is an Acantholytic Acanthoma?
Acantholytic dyskeratotic acanthoma (ADA) is a rare benign condition characterized by circumscribed epidermal proliferation displaying both acantholysis and dyskeratosis. Most cases are clinically diagnosed as basal cell carcinoma, which leads to their excision and histopathologic examination.
What is Acantholytic dyskeratosis?
Acantholytic dyskeratosis is a histopathologic pattern defined by a hyperkeratotic and parakeratotic epidermis with intraepidermal clefts containing acantholytic and dyskeratotic keratinocytes.
What does Acantholysis mean?
Acantholysis means loss of coherence between epidermal cells due to the breakdown of intercellular bridges. It is an important pathogenetic mechanism underlying various bullous disorders, particularly the pemphigus group, as well as many non-blistering disorders.
What is warty Dyskeratoma?
Warty dyskeratoma (WD) is a benign epidermal proliferation first reported in 1957 because of its distinctive histologic findings. WD presents as an umbilicated papule with a keratotic plug, usually limited to the head, neck, or face.
Is clear cell Acanthoma benign?
Clear cell acanthoma (CCA) is an uncommon, benign epidermal tumor that may be easily misdiagnosed on a clinical basis alone. Although biopsy is commonly performed for diagnosis, perceptive clinicians may suspect a CCA with the use of clinical and dermoscopic findings.
Why is it called Grover’s disease?
The exact cause of Grover’s disease is not known. It may be related to fragility of old sun-damaged skin. Some doctors feel that this skin disorder may be related to heat and sweating.
Is Grover’s disease serious?
A Grover’s disease rash and the itching that accompanies it can lower a person’s quality of life. The good news is that the disease is not life-threatening and usually goes away in 6–12 months. Dermatologists can help people to manage the condition and control their symptoms.
What is Hailey Hailey skin condition?
Hailey-Hailey disease, also known as benign chronic pemphigus, is a rare skin condition that usually appears in early adulthood. The disorder is characterized by red, raw, and blistered areas of skin that occur most often in skin folds, such as the groin, armpits, neck, and under the breasts.
What is Acantholytic keratosis?
Background: Acantholytic squamous cell carcinoma (aSCC) is regarded as a high-risk variant of cutaneous squamous cell carcinoma (SCC). Acantholytic actinic keratosis (aAK) has been regarded as a precursor risk factor for aSCC. However, supporting evidence is limited.
What is Corps Ronds?
Corps ronds refer to cells with small pyknotic nuclei, a perinuclear clear halo and eosinophilic cytoplasm (Figures 4 and 5). Grains are compressed cells with elongated nuclei seen in the stratum corneum and granular layer (Figures 4 and 5).
What is the meaning of warty?
Definition of ‘warty’ 1. having warts; covered with or as with warts. 2. resembling a wart.
